MovDisordV3, France, Analysis, bibRecord, 000656

Corticobasal degeneration: Decreased and asymmetrical glucose consumption as studied with PET

Identifieur interne : 000656 ( France/Analysis ); précédent : 000655; suivant : 000657

Corticobasal degeneration: Decreased and asymmetrical glucose consumption as studied with PET

Auteurs : Blin [France] ; M. Vidailhet [France] ; B. Pillon [France] ; Bruno Dubois [France] ; J. Feve [France] ; Yves Agid [France]

Source :

Movement Disorders [ 0885-3185 ] ; 1992.

RBID : ISTEX:592DF06A54C53856129653AB8AB1364CD98721EC

English descriptors

KwdEn :
- Aged, Apraxia, Apraxias (radionuclide imaging), Blood Glucose (metabolism), Brain Mapping, Cerebral Cortex (radionuclide imaging), Corpus Striatum (radionuclide imaging), Corticobasal degeneration, Deoxyglucose (analogs & derivatives), Deoxyglucose (metabolism), Dominance, Cerebral (physiology), Energy Metabolism (physiology), Female, Fluorodeoxyglucose, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Movement Disorders (radionuclide imaging), Muscle Rigidity (radionuclide imaging), Nerve Degeneration (physiology), Positron emission tomography, Substantia Nigra (radionuclide imaging), Thalamic Nuclei (radionuclide imaging), Tomography, Emission-Computed.
MESH :
- chemical , analogs & derivatives : Deoxyglucose.
- chemical , metabolism : Blood Glucose, Deoxyglucose.
- physiology : Dominance, Cerebral, Energy Metabolism, Nerve Degeneration.
- radionuclide imaging : Apraxias, Cerebral Cortex, Corpus Striatum, Movement Disorders, Muscle Rigidity, Substantia Nigra, Thalamic Nuclei.
- Aged, Brain Mapping, Female, Fluorodeoxyglucose F18, Humans, Male, Middle Aged, Tomography, Emission-Computed.

Abstract

Cerebral energy metabolism was studied by positron emission tomography and [18F]fluorodeoxyglucose in five patients with clinical diagnoses of probable corticobasal degeneration. A reduction in glucose consumption was observed in most cortical and subcortical structures compared to agematched controls. The reduction was greatest on the side of the brain contralateral to the most affected limbs, as shown by the significantly lower ratios of contralateral to homolateral metabolic rates, in the temporal and sensorimotor cortex of patients compared to controls. A distinct asymmetry between the two hemispheres could be observed in a patient who was examined twice in the course of his illness. Detection of this asymmetrical decrease in brain cortical and subcortical glucose metabolism may prove useful as additional evidence supporting clinical diagnoses of the disease.

Url:

https://api.istex.fr/document/592DF06A54C53856129653AB8AB1364CD98721EC/fulltext/pdf

DOI: 10.1002/mds.870070409

Affiliations:

Links to Exploration step

ISTEX:592DF06A54C53856129653AB8AB1364CD98721EC

Le document en format XML

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<author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M." last="Vidailhet">M. Vidailhet</name>
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<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B." last="Pillon">B. Pillon</name>
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<author><name sortKey="Dubois, Bruno" sort="Dubois, Bruno" uniqKey="Dubois B" first="Bruno" last="Dubois">Bruno Dubois</name>
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<author><name sortKey="Feve, J" sort="Feve, J" uniqKey="Feve J" first="J." last="Feve">J. Feve</name>
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<term>Brain Mapping</term>
<term>Cerebral Cortex (radionuclide imaging)</term>
<term>Corpus Striatum (radionuclide imaging)</term>
<term>Corticobasal degeneration</term>
<term>Deoxyglucose (analogs & derivatives)</term>
<term>Deoxyglucose (metabolism)</term>
<term>Dominance, Cerebral (physiology)</term>
<term>Energy Metabolism (physiology)</term>
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<term>Movement Disorders (radionuclide imaging)</term>
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<term>Nerve Degeneration (physiology)</term>
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<front><div type="abstract" xml:lang="en">Cerebral energy metabolism was studied by positron emission tomography and [18F]fluorodeoxyglucose in five patients with clinical diagnoses of probable corticobasal degeneration. A reduction in glucose consumption was observed in most cortical and subcortical structures compared to agematched controls. The reduction was greatest on the side of the brain contralateral to the most affected limbs, as shown by the significantly lower ratios of contralateral to homolateral metabolic rates, in the temporal and sensorimotor cortex of patients compared to controls. A distinct asymmetry between the two hemispheres could be observed in a patient who was examined twice in the course of his illness. Detection of this asymmetrical decrease in brain cortical and subcortical glucose metabolism may prove useful as additional evidence supporting clinical diagnoses of the disease.</div>
</front>
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Movement Disorders (revue)

Corticobasal degeneration: Decreased and asymmetrical glucose consumption as studied with PET

Corticobasal degeneration: Decreased and asymmetrical glucose consumption as studied with PET

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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